n=9 for c and d, except for Visit-3 where one Obese-IR did not attend. Data are presented as individual data points for each participant. ![]() (d) Weight of participants, divided by experimental groups, at each study visit. (c) HbA1c values of participants, divided by experimental groups, at each study visit. (b) The experimental plan was implemented in three visits: screening and collection of information of participants was performed at visit-1 blood and abdominal subcutaneous adipose tissue interstitial dialysate fluids were collected after an overnight fasting and during an oral glucose tolerance test (OGTT), and abdominal subcutaneous adipose tissue blood flow (ATBF) measurements (by 133Xe-clearance technique) were performed at visit-2 EndoPAT (peripheral arterial tone) measurements of endothelial function and subcutaneous adipose tissue biopsies collection were performed at visit-3. (a) Illustration of the volunteer selection procedure for the MD-Lipolysis study by specific inclusion (green) and exclusion (red) criteria, which defined the experimental groups: Lean Obese-IR and Obese-T2D.
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